Acarbose API Supplier

Xi'an Yihui Kambani inyanzvi inogadzira Acarbose. Tinogona kugadzira Acarbose ine 99.9% yemukati. Inogona kushandiswa muchikafu, mushonga, zvinhu zvehutano, kana zvigadzirwa zvekuzora, uye kusangana neUSP, BP, EP, CP zviyero. Tinogona kukupa zvigadzirwa zvemhando yepamusoro pamitengo inokwikwidza. Yako yakanakisa sarudzo kune ane mukurumbira yakachena Acarbose mutengesi ndeye Xi'an Yihui Kambani!

Chii chinonzi Acarbose API?

Purogiramu inonzi Acarbose, organic compound ine kemikari formula C25H43NO18 uye CAS Nha. 56180-94-0.Ichena kana chena-yakafanana, crystalline powder, isinganhuhwi, inovava zvishoma, inonyungudika mumvura. Zita remakemikari reacarbose ndi4, 6-o-ethyl mannitol-keto-alpha-d-glucose.

Acarbose API chinhu chinoshanda che alpha-glucosidase inhibitor zvinodhaka, zvinowanzogadzirwa muindasitiri ne microbial fermentation, senge actinomyces. Maitiro ekugadzira anonyanya kusanganisira hutachiona tsika, sero kuparadzaniswa uye kucheneswa, reactor yekudyisa maitiro uye kudhirowa, kupatsanurwa kwechigadzirwa uye kucheneswa, uye mamwe nhanho, pakati peiyo reactor yekudyisa reaction ndiyo nhanho yakakosha yekugadzirira carboxylate kubva kuglucose. Inonyanya kushandiswa kurapa Type 2 chirwere cheshuga.

Basic Information

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Chii Chinoshandiswa Acarbose?

Purogiramu inonzi Acarbose mushonga unozivikanwa unonyanya kushandiswa kurapa chirwere cheshuga cherudzi rwechipiri. Kunyanya, inorondedzerwa se nascence-glucosidase asset uye inobata mudumbu mudiki kuderedza kuparara uye kunyudzwa kwemacarbohydrates. Mushonga uyu unowanzo kutsanangurwa sechibatanidzwa chekudya uye maekisesaizi uye unowanzoshandiswa pamwe chete nezvimwe zvechirwere cheshuga.

inoshanda nekudzivisa ma enzymes anowanzo kuputsa makabhohaidhiretsi akaoma mushuga iri nyore, yakafanana neglucose. Nekudzikisa pasi kugaya uye kunyudzwa kweshuga idzi, zvinobatsira kudzora mamiriro ehuga muropa muvanhu vane chirwere cheshuga. Izvi zvinogona kubatsira kubatsira matambudziko uye kugadzirisa hutano hwakakwana.

Pamusoro pekurapa chirwere cheshuga cherudzi rwechipiri, yakadzidzwawo nekuda kwekushandiswa kwayo mukuderedza kutyisidzira kwekunyunyuta kwemoyo uye mamwe matambudziko emwoyo. Kumwe kuongorora kwakaratidza kuti mushonga uyu unogona kubatsira kunatsiridza lipid biographies uye kuderedza kuzvimba mumuviri, izvo zvinogona kutungamira mukuderedzwa kwekutyisidzira kwekunyunyuta kwemoyo nekufamba kwenguva.

Kumwe kushandiswa kwayo kwakajeka kunogona kusanganisira kurapwa kwemamwe mamiriro ane chekuita ne insulin kuramba, yakafanana ne polycystic ovary pateni (PCOS) uye metabolic pateni. zvakadaro, kumwe kuongorora kunodiwa kushandiswa kwakajeka uku kusati kwanyatsonzwisiswa.

Pakazara, mushonga unokosha wekurapa chirwere cheshuga chechipiri uye mamwe mamiriro akabatana. Nekudzikisa kunyudzwa kwemakabhohaidhiretsi uye kubatsira kudzora mamiriro eshuga yeropa, mushonga uyu unogona kubatsira kuderedza kutyisidzira kwezvinetso uye kugadzirisa hutano hwese. Nekudaro, taura kune wako croaker nezvekuti ingave yakanaka kurapwa sarudzo kwauri, Kana iwe wakaonekwa uine Type 2 chirwere cheshuga kana chimwe chakabatana mamiriro.

Kugadzirira

Iyo synthesis process ye Acarbose inogona kupfupikiswa mumatanho matatu anotevera:

1. Synthesis of aminocyclitol: Sedoheptulose-7-phosphate inosangana nemhinduro dze enzymatic dzinosanganisira intramolecular cyclization, epimerization, dehydrogenation, dehumidification, phosphorylation, uye nucleotidylation kubudisa NDP-1-epi-valienol-7-phosphate.

2. Synthesis ye4-amino-4,6-dideoxyglucose: D-glucose-1-phosphate inoshandurwa kuita dTDP kuburikidza nenyucleotidylation, dehumidification, uye transamination.

3. Synthesis of acarviosyl moiety: NDP-1-epi-valienol-7-phosphate uye dTDP inotambura neshuga yekufambisa mhinduro inopindirana ne glycosyltransferase kuti iite dTDP- acarbose-7-phosphate, iyo inobatanidza zvakananga ne maltose kuti iite acarbose-7-phosphate. Acarbose-7-phosphate inogadzirwa mukati mesero, asi kuti pakupedzisira ibudise acarbose, inoda kutakurwa kunze kwesero kuburikidza ne transmembrane protein AcbWXY/GacWXY uye kuita dephosphorylation.

Chii chinonzi Side Eeffects kune Acarbose?

Acarbose mushonga unoshandiswa mukurapa chirwere cheshuga chechipiri. Kunyange zvazvo mushonga uyu uchishanda mukudzora shuga yeropa, une zvakare akati wandei akapihwa zvinhu zveparutivi izvo zvingave zvine chekuita nenyaya. Zvimwe zvezvinhu zvakajairika zveparutivi zve Acarbose anti kuchembera anotaurwa pazasi

1. Matambudziko emudumbu: Inogona kubereka kuzvimba, gasi, uye manyoka. Aya matambudziko ekugaya anogona kunyanya kunetsa kune avo vaimbosangana nenyaya dzegastrointestinal.

2. Shuga yakaderera muropa: Inogona kubereka hypoglycemia, iyo inoratidzirwa nemamiriro eshuga shoma. Mhosva dzinotora mushonga uyu dzinofanirwa kutya zviratidzo uye zviratidzo zve hypoglycemia uye dzinofanira kudya nguva dzose, kudya kwakadzikama kudzivirira iyi mhedzisiro.

3. Zvinetso zvechiropa: Inogona kubereka kukuvara kwechiropa muzviitiko zvisingawanzoitiki. Mhosva dzinotora mushonga uyu dzinofanirwa kuve nechiropa chavo chakavharwa nguva dzose.

4. Mapundu paganda: Dzimwe nguva anogona kuita mapundu paanenge achiatora. Nepo chiratidzo ichi kazhinji chakapfava, nyaya dzinofanirwa kuzivisa croaker yavo kana vakapupurira chero shanduko nyowani kana isina kujairika yeganda.

5. Allergic reactions: Zvimwe zviitiko zvinogona kupupurira mhinduro isinganzwisisike kune acarbose. Zviratidzo zvinogona kusanganisira kunetseka kufema, mikoko, kana kuzvimba kwechiso nehuro. Mhosva dzinofanirwa kutsvaga kurapwa zvisingaite kana vakaona chimwe chezviratidzo izvi.

6. Flatulence: Yave ichizivikanwa kuti inokonzera kuwedzera flatulence kana kupfuura kwegasi. Ichi chiratidzo chinogona kushungurudza vamwe varwere asi kazhinji hachikuvadzi.
7. Kuvhiringidza kwekudya kwekudya: Inogona kukanganisa kubatwa kwezvimwe zvinovaka muviri, zvakadai se calcium uye vitamin D. Varwere vanotora mishonga iyi vanofanira kudya kudya kwakapfuma mune izvi zvinovaka muviri kana kutora kuwedzera kuti varege kukanganisa.
Zvakakosha kuti varwere vanotora acarbose vazive izvi zvinogona kuitika uye kukurukura chero zvinonetsa nachiremba wavo. Kana chimwe chezviratidzo izvi chikakura kana kuramba chichienderera mberi, varwere vanofanira kutsvaga kurapwa nekukasika. Pakazere, acarbose mushonga unobatsira wekudzora mazinga eshuga muropa muvarwere vane Type 2 chirwere cheshuga, asi zvakakosha kuziva nezvezvingangoita mhedzisiro.

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In mhedziso

Kupfupisa, Xi 'an Yihui Kambani senyanzvi yekugadzira Purogiramu inonzi Acarbose , ine zvigadzirwa zvemhando yepamusoro, yakakwirira yekutsvagisa uye kugona kusimudzira, zvemhando yepamusoro zvigadzirwa zvekugadzira uye tekinoroji, yakakwana mushure mekutengesa sevhisi uye zvimwe zvakanakira, isarudzo yemutengi yemudiwa akakodzera.

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